Nice lecture about Dirac.
If you prefer to read, this 1939 paper by Dirac is a characteristically lucid discussion of similar themes:
The Relation between Mathematics and Physics [PDF]
http://mcs.une.edu.au/~pmth213/PapersOfInterest/Paul%20Dirac...
Recently learned of this from the german-spoken podcast AstroGeo. If someone wants to listen to this Large Numbers Hypothesis story in podcast form, I enjoyed that episode: https://astrogeo.de/expandierende-erde-zu-grosse-zahlen-und-... (no affiliation)
See also perhaps the 1960 article/essay "The Unreasonable Effectiveness of Mathematics in the Natural Sciences":
* https://en.wikipedia.org/wiki/The_Unreasonable_Effectiveness...
Wonderful talk. I now have some reading material for the next week :)